A-953227 [1037826-77-9]
HY-114584
CAS Number1037826-77-9
Product group Chemicals
Molecular Weight457.46
Overview
- SupplierMedChem Express
- Product NameA-953227 [1037826-77-9]
- Delivery Days Customer9
- CAS Number1037826-77-9
- CertificationResearch Use Only
- Molecular FormulaC25H20FN5O3
- Molecular Weight457.46
- Scientific DescriptionA-953227 is a highly potent and selective inhibitor with the activity of inhibiting calcium-dependent esterase (calpain). A-953227 has enhanced selectivity for related cysteine proteases (cathepsins) and has shown good efficacy in cell experiments. A-953227 has shown broad efficacy in preclinical models for Alzheimers disease, suggesting that it has potential benefits in inhibiting Alzheimers disease[1].
- SMILESO=C(C1=C(N=CC=C1)N2N=C(C=C2)C3=CC=C(C=C3)F)NC(CC4=CC=CC=C4)C(C(N)=O)=O
- UNSPSC12352200