A01 --- Smurf1 E3 Ubiquitin Ligase Inhibitor

Bioss

A01 --- Smurf1 E3 Ubiquitin Ligase Inhibitor

16

Research Use Only

98.0

A01 is a potent and selective Smurf1 E3 ubiquitin ligase inhibitor with Kd ~3.7 nM. It attenuates Smurf1-mediated Smad 1/5 degradation and enhances BMP signaling. It also potentiates BMP-2-induced osteoblastic activity in C2C12 myoblasts and MC3T3-E1 osteoblast precursor cells.

-20°C

51202000