Bio-Connect

A2AAR/hMAO-B-IN-1 [1439488-21-7]

HY-120826
MedChem Express
CAS Number1439488-21-7
Product group Chemicals
Estimated Purity99.0
Molecular Weight324.40
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Overview

  • Supplier
    MedChem Express
  • Product Name
    A2AAR/hMAO-B-IN-1 [1439488-21-7]
  • Delivery Days Customer
    5
  • CAS Number
    1439488-21-7
  • Certification
    Research Use Only
  • Estimated Purity
    99.0
  • Molecular Formula
    C18H16N2O2S
  • Molecular Weight
    324.40
  • Scientific Description
    A2AAR/hMAO-B-IN-1 (compoudn 17) is a non-xanthine dual-target inhibitor targeting the A2A adenosine receptor (A2AAR) (IC50: 34.9 nM) andMAO-B (Ki: 39.5 nM, human). A2AAR/hMAO-B-IN-1 inhibits A2AAR-induced cAMP accumulation and exhibits competitive, reversible inhibition of MAO-B. A2AAR/hMAO-B-IN-1 can be used in the study of neurodegenerative diseases such as Parkinsons disease (PD)[1].
  • SMILES
    O=C1SC(NC(CCCC2=CC=CC=C2)=O)=NC3=C1C=CC=C3
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200