A71378 [127902-33-4]

MedChem Express

A71378 [127902-33-4]

5

127902-33-4

Research Use Only

C48H62N8O13S

991.12

A71378 is a selectivity CCK-A receptor agonist the IC50 values of 0.4 nM, 300 nM, and 1,200 nM for the pancreatic CCK-A, cortical CCK-B, and gastrin receptor, respectively. A71378 elicits pancreatic amylase secretion (EC50 = 0.16 nM) and ileal muscle contraction (EC50 = 3.7 nM)[1].

NC([C@H](CC1=CC=CC=C1)NC([C@H](CC(O)=O)N(C)C([C@H](CCCC)NC([C@@H](NC(CNC([C@H](CCCC)NC(CCC2=CC=C(C=C2)OS(=O)(O)=O)=O)=O)=O)CC3=CNC4=CC=CC=C34)=O)=O)=O)=O

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