AAK1 blocking peptide

GeneTex

AAK1 blocking peptide

9

Neutralisation/Blocking

Research Use Only

200 ug/ml

Unconjugated

AAK1

AP2 associated kinase 1

AP2-associated protein kinase 1, adaptor-associated kinase 1, alternative protein AAK1

Adaptor-related protein complex 2 (AP-2 complexes) functions during receptor-mediated endocytosis to trigger clathrin assembly, interact with membrane-bound receptors, and recruit encodytic accessory factors. This gene encodes a member of the SNF1 subfamily of Ser/Thr protein kinases. The protein interacts with and phosphorylates a subunit of the AP-2 complex, which promotes binding of AP-2 to sorting signals found in membrane-bound receptors and subsequent receptor endocytosis. Its kinase activity is stimulated by clathrin. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]

-20°C

41116100

Human