AB-680

MedChem Express

AB-680 [2105904-82-1]

10

2105904-82-1

Research Use Only

99.71

C20H24ClFN4O9P2

580.82

AB-680 is a highly potent, reversible and selective inhibitor of CD73 (an ecto-nucleotidase), with a K i of 4.9 pM for hCD73, displays >10,000-fold selectivity over related ecto-nucleotidases CD39. Anti-tumor activity [1] .

O=P(CP(O)(O)=O)(O)OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C(N=C(Cl)C=C3N[C@H](C4=CC=CC=C4F)C)=C3C=N2)O1

-20°C

12352200