Ab-Capcher

Cosmo Bio USA

Ab-Capcher

16

Research Use Only

IgG Purification Tool Beyond Protein A and G Ab-Capcher™ is ProteoNovas patented Protein A-R28 (Protein A variant) bound at high density to a supporting gel matrix offering many practical advantages for the routine purification of rat and mouse IgG including broader subclass specificity and high capacity binding. Ab-Rapid PuRE™ is a specially designed syringe-type column unit prepacked with AbCapcher offering maximum convenience for Ig purification. Ab-Rapid SPiN™ is a convenient spin column prepacked with Ab-Capcher. Protein A-R28 is an alkali-tolerant IgG-binding protein derived from protein A, which is developed with ProteNovas patent technology. Protein A-R28 strongly binds to various species and subclasses of IgG, compared with Protein A and G. The coupling to resin (Ab-Capcher) provides an alkali-washable unique affinity medium with high binding capacity for immunoglobulin, which is useful for purification of human, rabbit, and mouse IgGs including mouse IgG1. Ab-Aapcher is alsouseful for immuno-precipitation experiments. Features and Advantages: 1.) 5 times the binding capacity of Protein G 2.) Labile antibodies can be bound at neutral pH 3.) Low non-specific binding 4.) IgG puirty >95%

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