AB05831 [105265-96-1]

TargetMol Chemicals

AB05831 [105265-96-1]

72

105265-96-1

Research Use Only

AB05831

C8H16N2O4

204.22

AB05831, also known as 2-Acetamido-1,2-dideoxynojirimycin, is a highly potent and specific inhibitor of beta-hexosaminidase. N-Acetyl-3-hexosaminidase (HEX) is a member of lysosomal hydrolases, which catalyzes hydrolysis of terminal, non-reducing N-acetyl- - 3-D-glucosamine (GlcNAc) andN-acetyl-(3-D-galactosamine (GalNAc) residues in glycoproteins, gan-gliosides, and glycosaminoglycans (GAGs). HEX, released by chondrocytes into the extracellular compartment, promotes cartilage matrix degradation. Osteoarthritis patients have increased HEX activity in synovial fluid.

3 years

N(C(C)=O)[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)NC1

-20°C

12352200