ABC 1183

Biorbyt

ABC 1183

10

Research Use Only

C18H14N4OS

334.397

ABC1183 is a potent, selective, orally active GSK3alpha/beta and CDK9 inhibitor with IC50 of 327/657 nM and 321 nM (CDK9/cyclin T1), shows growth inhibitory activity against a broad panel of cancer cell lines; decreases cell survival through G2/M arrest and modu

N#CC1=CC=C(C(C2=C(N)N=C(NC3=CC=C(C)C=C3)S2)=O)C=C1

12352200