ABCA1 antibody [5A1-1422] (PE)

GeneTex

ABCA1 antibody [5A1-1422] (PE)

9

Flow Cytometry

Research Use Only

Monoclonal

5A1-1422

RPE

Abca1

ATP-binding cassette, sub-family A (ABC1), member 1

ABC; Abc1; ABC-1; ATP-binding cassette 1; ATP-binding cassette sub-family A member 1; ATP-binding cassette transporter 1; phospholipid-transporting ATPase ABCA1

Rat

IgG2a

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. In humans, this protein functions as a cholesterol efflux pump in the cellular lipid removal pathway. Mutations in the human gene have been associated with Tangiers disease and familial high-density lipoprotein deficiency. [provided by RefSeq, Jul 2008]

Mouse

2°C to 8°C

12352203