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Western blot using GeneTexs affinity purified anti-ABCB6 antibody (right panel, lane B6) shows detection of Flag tagged human ABCB6 protein at 104 kDa and a truncated form of the protein at 79 kDa (arrowheads). The antibody successfully detected ABCB6 in KB cells transfected with the ABCB6 protein. A lysate prepared from KB cells without a vector insert (CV lane) should no reactivity with the antibody. The left panel shows a similar staining pattern using an anti-Flag? antibody as a positive control. The membrane was probed with the primary antibody diluted to 1:1,400.
Western blot using GeneTexs affinity purified anti-ABCB6 antibody (right panel, lane B6) shows detection of Flag tagged human ABCB6 protein at 104 kDa and a truncated form of the protein at 79 kDa (arrowheads). The antibody successfully detected ABCB6 in KB cells transfected with the ABCB6 protein. A lysate prepared from KB cells without a vector insert (CV lane) should no reactivity with the antibody. The left panel shows a similar staining pattern using an anti-Flag? antibody as a positive control. The membrane was probed with the primary antibody diluted to 1:1,400.
Western blot using GeneTexs affinity purified anti-ABCB6 antibody (right panel, lane B6) shows detection of Flag tagged human ABCB6 protein at 104 kDa and a truncated form of the protein at 79 kDa (arrowheads). The antibody successfully detected ABCB6 in KB cells transfected with the ABCB6 protein. A lysate prepared from KB cells without a vector insert (CV lane) should no reactivity with the antibody. The left panel shows a similar staining pattern using an anti-Flag? antibody as a positive control. The membrane was probed with the primary antibody diluted to 1:1,400.

ABCB6 antibody

GTX48698
GeneTex
ApplicationsWestern Blot, ELISA
Product group Antibodies
TargetABCB6
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Overview

  • Supplier
    GeneTex
  • Product Name
    ABCB6 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:1000-1:5000. ELISA: 1:40000-1:130000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ELISA
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID10058
  • Target name
    ABCB6
  • Target description
    ATP binding cassette subfamily B member 6 (Langereis blood group)
  • Target synonyms
    ABC; ABC-type heme transporter ABCB6; ATP-binding cassette half-transporter; ATP-binding cassette sub-family B member 6; ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group); LAN; mitochondrial ABC transporter 3; mt-ABC transporter 3; MTABC3; P-glycoprotein-related protein; PRP; truncated ATP binding cassette subfamily b member 6; ubiquitously-expressed mammalian ABC half transporter; umat
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ9NP58
  • Protein Name
    ATP-binding cassette sub-family B member 6, mitochondrial
  • Scientific Description
    ABCB6 (ATP-binding cassette sub-family B member 6, also known as mitochondrial precursor ABC transporter 3, Mt-ABC transporter 3, and ABC transporter umat) is a member of the superfamily of ATP-binding cassette (ABC) transporters.ABCB6 is a membrane-associated protein that transports various molecules across the extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, DR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily confer multi-drug resistance (MDR) to cancer cells and are also involved in antigen presentation. ABCB6 also likely plays a role in mitochondrial function. Localized to 2q26, this gene is considered a candidate gene for lethal neonatal metabolic syndrome, a disorder of mitochondrial function.
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

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