Western blot using GeneTexs affinity purified anti-ABCB6 antibody (right panel, lane B6) shows detection of Flag tagged human ABCB6 protein at 104 kDa and a truncated form of the protein at 79 kDa (arrowheads). The antibody successfully detected ABCB6 in KB cells transfected with the ABCB6 protein. A lysate prepared from KB cells without a vector insert (CV lane) should no reactivity with the antibody. The left panel shows a similar staining pattern using an anti-Flag? antibody as a positive control. The membrane was probed with the primary antibody diluted to 1:1,400.
Western blot using GeneTexs affinity purified anti-ABCB6 antibody (right panel, lane B6) shows detection of Flag tagged human ABCB6 protein at 104 kDa and a truncated form of the protein at 79 kDa (arrowheads). The antibody successfully detected ABCB6 in KB cells transfected with the ABCB6 protein. A lysate prepared from KB cells without a vector insert (CV lane) should no reactivity with the antibody. The left panel shows a similar staining pattern using an anti-Flag? antibody as a positive control. The membrane was probed with the primary antibody diluted to 1:1,400.
ABCB6 antibody
GTX48698
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityCanine, Human
TargetABCB6
Overview
- SupplierGeneTex
- Product NameABCB6 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:1000-1:5000. ELISA: 1:40000-1:130000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- FormulationLiquid
- Gene ID10058
- Target nameABCB6
- Target descriptionATP binding cassette subfamily B member 6 (Langereis blood group)
- Target synonymsABC; ABC-type heme transporter ABCB6; ATP-binding cassette half-transporter; ATP-binding cassette sub-family B member 6; ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group); LAN; mitochondrial ABC transporter 3; mt-ABC transporter 3; MTABC3; P-glycoprotein-related protein; PRP; truncated ATP binding cassette subfamily b member 6; ubiquitously-expressed mammalian ABC half transporter; umat
- HostRabbit
- IsotypeIgG
- Protein IDQ9NP58
- Protein NameATP-binding cassette sub-family B member 6, mitochondrial
- Scientific DescriptionABCB6 (ATP-binding cassette sub-family B member 6, also known as mitochondrial precursor ABC transporter 3, Mt-ABC transporter 3, and ABC transporter umat) is a member of the superfamily of ATP-binding cassette (ABC) transporters.ABCB6 is a membrane-associated protein that transports various molecules across the extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, DR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily confer multi-drug resistance (MDR) to cancer cells and are also involved in antigen presentation. ABCB6 also likely plays a role in mitochondrial function. Localized to 2q26, this gene is considered a candidate gene for lethal neonatal metabolic syndrome, a disorder of mitochondrial function.
- ReactivityCanine, Human
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203