Bio-Connect

ABCB7 antibody [C1C3]

GTX114916
GeneTex
ApplicationsWestern Blot
Product group Antibodies
TargetABCB7
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Overview

  • Supplier
    GeneTex
  • Product Name
    ABCB7 antibody [C1C3]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1.2 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID22
  • Target name
    ABCB7
  • Target description
    ATP binding cassette subfamily B member 7
  • Target synonyms
    ABC7, ASAT, Atm1p, EST140535, iron-sulfur clusters transporter ABCB7, mitochondrial, ABC transporter 7 protein, ATP-binding cassette sub-family B member 7, mitochondrial, ATP-binding cassette transporter 7, ATP-binding cassette, sub-family B (MDR/TAP), member 7
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDO75027
  • Protein Name
    Iron-sulfur clusters transporter ABCB7, mitochondrial
  • Scientific Description
    The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a half-transporter involved in the transport of heme from the mitochondria to the cytosol. With iron/sulfur cluster precursors as its substrates, this protein may play a role in metal homeostasis. Mutations in this gene have been implicated in X-linked sideroblastic anemia with ataxia. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Piel RB 3rd, Shiferaw MT, Vashisht AA, et al. A Novel Role for Progesterone Receptor Membrane Component 1 (PGRMC1): A Partner and Regulator of Ferrochelatase. Biochemistry. 2016,55(37):5204-17. doi: 10.1021/acs.biochem.6b00756
    Read this paper
  • Medlock AE, Shiferaw MT, Marcero JR, et al. Identification of the Mitochondrial Heme Metabolism Complex. PLoS One. 2015,10(8):e0135896. doi: 10.1371/journal.pone.0135896
    Read this paper