WB analysis of mouse peritoneal macrophages using GTX30598 ABCG1 antibody. Lane 1 : untreated mouse peritoneal macrophages (positive control) Lane 2 : 22-(R)-hydrocholesterol treated macrophages Lane 3 : T0901713 treated macrophages Lane 4 : T0901713 treated macrophages

ABCG1 antibody

GTX30598

ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin, Other Application

Product group Antibodies

TargetABCG1

Overview

Supplier
GeneTex
Product Name
ABCG1 antibody
Delivery Days Customer
9
Application Supplier Note
WB: 1:500. IHC-P: 1:100 - 1:400. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin, Other Application
Certification
Research Use Only
Clonality
Polyclonal
Concentration
1 mg/ml
Conjugate
Unconjugated
Gene ID9619
Target name
ABCG1
Target description
ATP binding cassette subfamily G member 1
Target synonyms
ABC8, WHITE1, ATP-binding cassette sub-family G member 1, ABC transporter 8, ATP-binding cassette transporter 8, ATP-binding cassette transporter member 1 of subfamily G, ATP-binding cassette, sub-family G (WHITE), member 1, homolog of Drosophila white, white protein homolog (ATP-binding cassette transporter 8)
Host
Rabbit
Isotype
IgG
Protein IDP45844
Protein Name
ATP-binding cassette sub-family G member 1
Scientific Description
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. It is involved in macrophage cholesterol and phospholipids transport, and may regulate cellular lipid homeostasis in other cell types. Six alternative splice variants have been identified. [provided by RefSeq]
Storage Instruction
2°C to 8°C
UNSPSC
12352203

References

Wang G, Chen JJ, Deng WY, et al. CTRP12 ameliorates atherosclerosis by promoting cholesterol efflux and inhibiting inflammatory response via the miR-155-5p/LXRα pathway. Cell Death Dis. 2021,12(3):254. doi: 10.1038/s41419-021-03544-8
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Sabeva NS, McPhaul CM, Li X, et al. Phytosterols differentially influence ABC transporter expression, cholesterol efflux and inflammatory cytokine secretion in macrophage foam cells. J Nutr Biochem. 2011,22(8):777-83. doi: 10.1016/j.jnutbio.2010.07.002
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ABCG1 antibody

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