WB analysis of mouse peritoneal macrophages using GTX30598 ABCG1 antibody. Lane 1 : untreated mouse peritoneal macrophages (positive control) Lane 2 : 22-(R)-hydrocholesterol treated macrophages Lane 3 : T0901713 treated macrophages Lane 4 : T0901713 treated macrophages
WB analysis of mouse peritoneal macrophages using GTX30598 ABCG1 antibody. Lane 1 : untreated mouse peritoneal macrophages (positive control) Lane 2 : 22-(R)-hydrocholesterol treated macrophages Lane 3 : T0901713 treated macrophages Lane 4 : T0901713 treated macrophages
ABCG1 antibody
GTX30598
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin, Other Application
Product group Antibodies
ReactivityHamster, Human, Monkey, Mouse, Rabbit, Rat
TargetABCG1
Overview
- SupplierGeneTex
- Product NameABCG1 antibody - Orthogonal Validated
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500. IHC-P: 1:100 - 1:400. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin, Other Application
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID9619
- Target nameABCG1
- Target descriptionATP binding cassette subfamily G member 1
- Target synonymsABC transporter 8; ABC8; ATP-binding cassette sub-family G member 1; ATP-binding cassette transporter 8; ATP-binding cassette transporter member 1 of subfamily G; ATP-binding cassette, sub-family G (WHITE), member 1; homolog of Drosophila white; white protein homolog (ATP-binding cassette transporter 8); WHITE1
- HostRabbit
- IsotypeIgG
- Protein IDP45844
- Protein NameATP-binding cassette sub-family G member 1
- Scientific DescriptionThe protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. It is involved in macrophage cholesterol and phospholipids transport, and may regulate cellular lipid homeostasis in other cell types. Six alternative splice variants have been identified. [provided by RefSeq]
- ReactivityHamster, Human, Monkey, Mouse, Rabbit, Rat
- Storage Instruction2°C to 8°C
- UNSPSC12352203
References
- CTRP12 ameliorates atherosclerosis by promoting cholesterol efflux and inhibiting inflammatory response via the miR-155-5p/LXRalpha pathway. Wang G et al., 2021 Mar 10, Cell Death DisRead more
- Phytosterols differentially influence ABC transporter expression, cholesterol efflux and inflammatory cytokine secretion in macrophage foam cells. Sabeva NS et al., 2011 Aug, J Nutr BiochemRead more