Bio-Connect

ABCG2-IN-3 [1942919-63-2]

HY-119724
MedChem Express
CAS Number1942919-63-2
Product group Chemicals
Molecular Weight451.34
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Overview

  • Supplier
    MedChem Express
  • Product Name
    ABCG2-IN-3 [1942919-63-2]
  • Delivery Days Customer
    5
  • CAS Number
    1942919-63-2
  • Certification
    Research Use Only
  • Molecular Formula
    C25H20Cl2N2O2
  • Molecular Weight
    451.34
  • Scientific Description
    ABCG2-IN-3 (Compound 52) is a selective inhibitor for breast cancer resistance protein (ABCG2), with an IC50 of 0.238 microM. ABCG2-IN-3 reverses the ABCG2-mediated resistance toward SN-38 and inhibit the ATPase activity[1].
  • SMILES
    COC1=CC=C(C=C1)C(N2C(C3=C(CC2)C(C=CC=C4)=C4N3)C5=CC(Cl)=C(C=C5)Cl)=O
  • UNSPSC
    12352200