Bio-Connect

ABD459 [1047670-51-8]

HY-118056
MedChem Express
CAS Number1047670-51-8
Product group Chemicals
Molecular Weight516.21
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Overview

  • Supplier
    MedChem Express
  • Product Name
    ABD459 [1047670-51-8]
  • Delivery Days Customer
    5
  • CAS Number
    1047670-51-8
  • Certification
    Research Use Only
  • Molecular Formula
    C24H17BrCl2N2O2
  • Molecular Weight
    516.21
  • Scientific Description
    ABD459 is a CB1 receptor antagonist with significant effects on regulating food intake and sleep-wake cycles. ABD459 completely displaces CB1 agonist CP99540 (Ki = 8.6 nM) and antagonizes CP55940-induced GTPgammaS binding (KB = 7.7 nM). ABD459 may specifically modulate endogenous cannabinoid release through cholinergic activity and plays a role in attention and arousal regulation. ABD459 is suitable for research in neurological disorders[1].
  • SMILES
    O=C(C1=NN(C(C2=CC=C(Br)C=C2)=C1C)C3=CC=C(C=C3Cl)Cl)C4=CC=C(C=C4)OC
  • UNSPSC
    12352200