Abemaciclib metabolite M2 [1231930-57-6]

MedChem Express

Abemaciclib metabolite M2 [1231930-57-6]

10

1231930-57-6

Research Use Only

99.75

C25H28F2N8

478.54

Abemaciclib metabolite M2 (LSN2839567) is a metabolite of Abemaciclib, acts as a potent CDK4 and CDK6 inhibitor, with IC50s of 1.2 and 1.3 nM, respectively. Anti-cancer activity[1][2].

CC(N1C2=CC(C3=NC(NC4=NC=C(CN5CCNCC5)C=C4)=NC=C3F)=CC(F)=C2N=C1C)C

-20°C,2°C to 8°C

12352200