Abeta-IN-1 [2766509-32-2]

TargetMol Chemicals

Abeta-IN-1 [2766509-32-2]

4

Chemical

Research Use Only

Abèta-IN-1

99.14%

C35H49N

483.77

Abeta-IN-1 is a novel, potent and orally active gamma-secretase modulator (GSM). Abeta-IN-1 potently reduced Abeta42 levels with an IC 50 value of 0.091 microM in cultured cells without inhibiting CYP3A4. Abeta-IN-1 shows a sustained pharmacokinetic profile.

3 years

C[C@@]12[C@@]3([C@]([C@]4([C@](C)(CC3)[C@@]([C@@H](CCCC(C)C)C)(CC4)[H])[H])(CC=C1C=5C(CC2)=NC=6C(C5C)=CC=CC6)[H])[H]

-20°C

51202000