ABHD12 Antibody

Cusabio

ABHD12 Antibody

20

ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

Unconjugated

ABHD12

abhydrolase domain containing 12, lysophospholipase

ABHD12A, BEM46L2, C20orf22, PHARC, dJ965G21.2, hABHD12, lysophosphatidylserine lipase ABHD12, 2-arachidonoylglycerol hydrolase ABHD12, abhydrolase domain-containing protein 12, monoacylglycerol lipase ABHD12, oxidized phosphatidylserine lipase ABHD12

Rabbit

IgG

Monoacylglycerol lipase ABHD12

This gene encodes an enzyme that catalyzes the hydrolysis of 2-arachidonoyl glycerol (2-AG), the main endocannabinoid lipid transmitter that acts on cannabinoid receptors, CB1 and CB2. The endocannabinoid system is involved in a wide range of physiological processes, including neurotransmission, mood, appetite, pain appreciation, addiction behavior, and inflammation. Mutations in this gene are associated with the neurodegenerative disease, PHARC (polyneuropathy, hearing loss, ataxia, retinitis pigmentosa, and cataract), resulting from an inborn error of endocannabinoid metabolism. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Human, Mouse, Rat

-20°C or -80°C

41116161