ABL (T315I) Assay Kit
79576
Product group Assays
Overview
- SupplierBPS Bioscience
- Product NameABL (T315I) Assay Kit
- Delivery Days Customer7
- CertificationResearch Use Only
- Scientific DescriptionThe Abelson (ABL) family of nonreceptor tyrosine kinases is critical to the progression and treatment of chronic myeloid leukemia (CML). The single-point mutation T315I has been linked to drug resistance and poor prognosis, making it an important drug target. The ABL (T315I) Assay Kit is designed to measure ABL activity for screening and profiling applications using Kinase-Glo® MAX as a detection reagent. The ABL (T315I) Assay Kit comes in a convenient 96-well format, with enough purified recombinant ABL enzyme, ABLtide peptide, ATP, and kinase assay buffer for 100 enzyme reactions.
- UNSPSC41116133
References
- Greuber, E. K., Smith-Pearson, P., Wang, J., & Pendergast, A. M. (2013). Role of ABL Family Kinases in Cancer: from Leukemia to Solid Tumors. Nature Reviews. Cancer, 13(8), 559-571
- Ganguly SS, Plattner R. (2012). Activation of Abl Family Kinases in Solid Tumors. Genes & Cancer 3(5-6):414-425
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Product group Chemicals
Staurosporine27002
CAS Number62996-74-1
Estimated Purity≥95%
Molecular Weight466.5 Da
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Product group Molecular Biology
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