Bio-Connect

Abrocitinib (Standard)

HY-107429R
MedChem Express
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Abrocitinib (Standard) [1622902-68-4]
  • Delivery Days Customer
    5
  • Certification
    Research Use Only
  • Scientific Description
    Abrocitinib (Standard) is the analytical standard of Abrocitinib. This product is intended for research and analytical applications. Abrocitinib (PF-04965842) is a potent, orally active and selective JAK1 inhibitor, with IC 50 s of 29 and 803 nM for JAK1 and JAK2, respectively. Abrocitinib (PF-04965842) exhibits less active effect on TYK2 ( IC 50 , 1.253 microM), and inhibits phosphorylation of STAT1, STAT3 and STAT5 after stimulation. Effective in autoimmune disease [1] .
  • UNSPSC
    41116135