Abrocitinib (Standard)
HY-107429R
Product group Assays
Overview
- SupplierMedChem Express
- Product NameAbrocitinib (Standard) [1622902-68-4]
- Delivery Days Customer5
- CertificationResearch Use Only
- Scientific DescriptionAbrocitinib (Standard) is the analytical standard of Abrocitinib. This product is intended for research and analytical applications. Abrocitinib (PF-04965842) is a potent, orally active and selective JAK1 inhibitor, with IC 50 s of 29 and 803 nM for JAK1 and JAK2, respectively. Abrocitinib (PF-04965842) exhibits less active effect on TYK2 ( IC 50 , 1.253 microM), and inhibits phosphorylation of STAT1, STAT3 and STAT5 after stimulation. Effective in autoimmune disease [1] .
- UNSPSC41116135