ABT-255 (free base) [186293-38-9]
HY-113619
CAS Number186293-38-9
Product group Chemicals
Molecular Weight385.43
Overview
- SupplierMedChem Express
- Product NameABT-255 (free base) [186293-38-9]
- Delivery Days Customer999
- CAS Number186293-38-9
- CertificationResearch Use Only
- Molecular FormulaC21H24FN3O3
- Molecular Weight385.43
- Scientific DescriptionABT-255 free base is an orally active anti-bacterial agent. ABT-255 free base exhibits potent in vitro potency (MIC = 0.016-0.031 microg/mL) against drug-susceptible and Rifampin (HY-B0272)- or Ethambutol (HY-B0535)-resistant Mycobacterium tuberculosis. ABT-255 free base shows efficacy against S. aureus, S. pneumoniae and E. coli and reduces viable counts of drug-resistant Mycobacterium tuberculosis in CF-1 mice. ABT-255 free base can be used for the study of pulmonary tuberculosis[1].
- SMILESO=C(C1=CC(C2CC2)=C3C(C)=C(N(C4)C[C@]5([H])[C@@]4([H])CCCN5)C(F)=CN3C1=O)O
- UNSPSC12352200