ABT-724 (trihydrochloride)

MedChem Express

ABT-724 (trihydrochloride) [587870-77-7]

10

587870-77-7

Research Use Only

99.05

C17H22Cl3N5

402.75

ABT-724 trihydrochloride is a potent and highly selective dopamine D 4 receptor agonist with an EC 50 of 12.4 nM for human dopamine D 4 receptor . ABT-724 trihydrochloride is a potent partial agonist at the rat D 4 ( EC 50 of 14.3 nM) and the ferret D 4 receptor ( EC 50 of 23.2 nM), and has no effect on dopamine D 1 , D 2 , D 3 , or D 5 receptors. ABT-724 trihydrochloride could be useful for the treatment of erectile dysfunction and has favorable side-effect profile [1] .

[H]Cl.[H]Cl.[H]Cl.C1(NC(CN2CCN(C3=NC=CC=C3)CC2)=N4)=C4C=CC=C1

2°C to 8°C

12352200