Ac-LEHD-AMC [292633-16-0]

MedChem Express

Ac-LEHD-AMC [292633-16-0]

10

292633-16-0

Research Use Only

98.96

C33H41N7O11

711.72

Ac-LEHD-AMC is a fluorogenic substrate for caspase-9 (Excitation: 341 nm; Emission: 441 nm). Caspase-9 can induce hydrolysis of Ac-LEHD-AMC, resulting in the release of AMC fluorophore and its fluorescence can be used to quantify caspase-9 activity[1].

CC(C1=CC=C(NC([C@H](CC(O)=O)NC([C@@H](NC([C@H](CCC(O)=O)NC([C@@H](NC(C)=O)CC(C)C)=O)=O)CC2=CN=CN2)=O)=O)C=C1O3)=CC3=O

-20°C

12162000