Ac-RLR-AMC (TFA)

MedChem Express

Ac-RLR-AMC (TFA)

5

Research Use Only

C30H46N10O6.xCF3COOH

642.8 (free base)

Ac-RLR-AMC (Ac-Arg-Leu-Arg-AMC) TFA is a fluorogenic substrate for the 26S proteasome (Ex/Em: 380/440-460 nm). AMC is released upon cleavage, and its fluorescence can be used to quantify the trypsin-like activity of 26S proteasomes[1].

O=C(O)C(F)(F)F.CC(C1=CC=C(NC([C@H](CCCNC(N)=N)NC([C@H](CC(C)C)NC([C@@H](NC(C)=O)CCCNC(N)=N)=O)=O)=O)C=C1O2)=CC2=O.[x]

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