Ac4GalNAz, N-azidoacetylgalactosamine-tetraacylated (Ac4GalNAz) [653600-56-7]

Jena Bioscience

Ac4GalNAz, N-azidoacetylgalactosamine-tetraacylated (Ac4GalNAz) [653600-56-7]

5

653600-56-7

Research Use Only

C16H22N4O10

430.37 g/mol

The tetraacetylated N-Azidoacetyl-galactosamine (Ac4GalNAz) provides a non-radioactive alternative for glycoconjugate visualization. It is cell-permeable, intracellularly processed and incorporated instead of its natural monosaccharide counterpart N-Acetylgalactosamine(GalNAc). The resulting Azide-functionalized glycoconjugates can subsequently be detected via Cu(I)-catalyzed or Cu(I)-free Click Chemistry that offers the choice to introduce a Biotin group (via Azides of Biotin or DBCO-containing Biotin, respectively) for subsequent purification tasks or to introduce fluorescent group (via Azides of fluorescent dyes or DBCO-containing fluorescent dyes, respectively) for subsequent microscopic imaging. Recommended concentration for metabolic labeling: 25-75 microM. This concentration range may serve as a starting point for an individual assay set-up.

[C@H]1([C@H](C(O[C@@H]([C@@H]1OC(=O)C)COC(=O)C)OC(=O)C)NC(=O)CN=[N+]=[N-])OC(=O)C

-20°C

12352200