Ac4ManNAz, N-azidoacetylatedmannosamine-tetraacylated (Ac4ManAz) [361154-30-5]

Jena Bioscience

Ac4ManNAz, N-azidoacetylatedmannosamine-tetraacylated (Ac4ManAz) [361154-30-5]

5

361154-30-5

Research Use Only

C16H22N4O10

430.37 g/mol

The tetraacetylated N-Azidoacetyl-mannosamine (Ac4ManNAz) provides a non-radioactive alternative for glycoconjugate visualization. It is cell-permeable, intracellularly processed and incorporated instead of its natural monosaccharide counterpart N-Acetylmannosamine(ManNAc). The resulting Azide-functionalized glycoconjugates can subsequently be detected via Cu(I)-catalyzed or Cu(I)-free Click Chemistry that offers the choice to introduce a Biotin group (via Azides of Biotin or DBCO-containing Biotin, respectively) for subsequent purification tasks or to introduce fluorescent group (via Azides of fluorescent dyes or DBCO-containing fluorescent dyes, respectively) for subsequent microscopic imaging. Recommended concentration for metabolic labeling: 25-75 microM. This concentration range may serve as a starting point for an individual assay set-up.

[C@H]1([C@@H](C(O[C@@H]([C@H]1OC(=O)C)COC(=O)C)OC(=O)C)NC(=O)CN=[N+]=[N-])OC(=O)C

-20°C

12352200