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Acalabrutinib-d3

HY-W757743
MedChem Express
Molecular Weight468.53
Product group Chemicals
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Acalabrutinib-d3
  • Delivery Days Customer
    14
  • Certification
    Research Use Only
  • Molecular Formula
    C26H20D3N7O2
  • Molecular Weight
    468.53
  • Scientific Description
    Acalabrutinib-d 3 (ACP-196-d 3 ) is the deuterated form of Acalabrutinib (HY-17600). Acalabrutinib (ACP-196) is an orally active, irreversible, highly selective second-generation BTK inhibitor. Acalabrutinib covalently binds to Cys481 in the ATP-binding pocket of BTK. Acalabrutinib shows strong targeting and efficacy in mouse models of chronic lymphocytic leukemia (CLL).
  • SMILES
    O=C(NC1=NC=CC=C1)C2=CC=C(C=C2)C3=C4C(N)=NC=CN4C([C@@H]5CCCN5C(C#CC([2H])([2H])[2H])=O)=N3
  • UNSPSC
    12352200