Western Blot Positive WB detected in: Mouse spleen tissue All lanes: ACD antibody at 4ug/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 58 kDa Observed band size: 58 kDa

ACD Antibody

Name: ACD Antibody
SKU: CSB-PA839289LA01HU_C90
Availability: BackOrder

CSB-PA839289LA01HU

ApplicationsWestern Blot, ELISA

Product group Antibodies

TargetACD

Overview

Supplier
Cusabio
Product Name
ACD Antibody
Delivery Days Customer
20
Applications
Western Blot, ELISA
Certification
Research Use Only
Clonality
Polyclonal
Conjugate
Unconjugated
Gene ID65057
Target name
ACD
Target description
ACD shelterin complex subunit and telomerase recruitment factor
Target synonyms
adrenocortical dysplasia homolog; adrenocortical dysplasia protein homolog; PIP1; POT1 and TIN2-interacting protein; PTOP; TIN2 interacting protein 1; TINT1; TPP1
Host
Rabbit
Isotype
IgG
Protein IDQ96AP0
Protein Name
Adrenocortical dysplasia protein homolog
Scientific Description
Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends. Without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Promotes binding of POT1 to single-stranded telomeric DNA. Modulates the inhibitory effects of POT1 on telomere elongation. The ACD-POT1 heterodimer enhances telomere elongation by recruiting telomerase to telomeres and increasing its processivity. May play a role in organogenesis.
Storage Instruction
-20°C or -80°C
UNSPSC
12352203

ACD Antibody

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Overview

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