Acetoacetic acid [541-50-4]

MedChem Express

Acetoacetic acid [541-50-4]

10

541-50-4

Research Use Only

95.0

C4H6O3

102.09

Acetoacetic acid is an oxidative stress inducer that affects the antioxidant enzyme system and lipoprotein metabolism. Acetoacetic acid induces oxidative stress by decreasing the mRNA expression and activity of superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-Px), increasing MDA content, and inhibiting very low density lipoprotein (VLDL) assembly by downregulating apolipoprotein ApoB100, ApoE, and low density lipoprotein receptor (LDLR), leading to triglyceride (TG) accumulation in hepatocytes. Acetoacetic acid can be used to study metabolic diseases[1][2][3].

CC(CC(O)=O)=O

-20°C,2°C to 8°C

12352200