AChE-IN-11

MedChem Express

AChE-IN-11

10

Research Use Only

C18H28N2O4

336.43

AChE-IN-11 (compound 5C) is a triple inhibitor targeting AChE/MAO-B/BACE1 ( IC 50 =7.9 microM, 9.9 microM, 8.3 microM, respectively) and a selective metal ion chelators. AChE-IN-11 exhibits mixed AChE inhibitory effects, binding to both CAS and PAS of AChE. AChE-IN-11 also exhibits good antioxidant activity (ORAC=2.5 eq) and potential neuroprotective effects in Alzheimers disease [1] .

[H][C@@](COC1=CC(O)=C(C=C1)C(C)=O)(CN2CCN(CC2)C(C)C)O

12352200