AChE-IN-14 [2390042-05-2]

MedChem Express

AChE-IN-14 [2390042-05-2]

10

2390042-05-2

Research Use Only

C28H35NO3

433.58

AChE-IN-14 (compound 5) is a potent cholinesterase inhibitor with IC50s of 0.46, 0.48, and 0.44 microM for electric eel acetylcholinesterase (eeAChE), human recombinant acetylcholinesterase (hAChE), and equine serum butyrylcholinesterase (eqBuChE), respectively. AChE-IN-14 exhibits high affinity toward human H3 receptor (H3R; Ki= 159.8 nM). AChE-IN-14 can be used for the research of Alzheimers disease[1].

O=C1C=C(C2=CC=C(OCCCCCCN3CCCCCC3)C=C2)OC4=CC=C(C)C=C14

12131703