AChE/BChE/MAO-B-IN-4

MedChem Express

AChE/BChE/MAO-B-IN-4

10

Research Use Only

C26H33N3O4

451.56

AChE/BChE/MAO-B-IN-4, an indan-1-one derivative, is a potent MAO-B inhibitor with an IC50 of 0.0393 microM for human MAO-B. AChE/BChE/MAO-B-IN-4 is a potent AChE and BChE enzyme inhibitor, with IC50s of 0.0458 microM and 0.075 microM for human AChE and BChE enzyme, respectively. AChE/BChE/MAO-B-IN-4 shows significant antioxidant activity and prevent beta-amyloid plaque aggregation. AChE/BChE/MAO-B-IN-4 has the potential for Alzheimers disease (AD) research[1].

O=C(NC1=CC=C(/C=C(CC2=C3C=C(OC)C(OC)=C2)\C3=O)C=C1)CN(C)CCCN(C)C

12131703