AChE/BuChE-IN-2 [1946008-31-6]

MedChem Express

AChE/BuChE-IN-2 [1946008-31-6]

10

1946008-31-6

Research Use Only

C20H18N2O2

318.37

AChE/BuChE-IN-2 (Compound 5f) is an orally active AChE and BuChE inhibitor with IC50 values of 0.72 microM and 0.16 microM, respectively. AChE/BuChE-IN-2 shows a non-competitive inhibition with AChE and shows potent self-induced beta-amyloid (Abeta) aggregation inhibition with an IC50 of 62.52 microM. AChE/BuChE-IN-2 can cross the BBB[1].

C1(C2=CC=C(OCO3)C3=C2)=NC4=CC=CC=C4C(N5CCCC5)=C1

12131703