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AChE/BuChE/MAO-B-IN-1

HY-151562
MedChem Express
Molecular Weight289.37
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Product group Chemicals
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Overview

  • Supplier
    MedChem Express
  • Product Name
    AChE/BuChE/MAO-B-IN-1 [2834758-29-9]
  • Delivery Days Customer
    10
  • Certification
    Research Use Only
  • Molecular Formula
    C17H23NO3
  • Molecular Weight
    289.37
  • Scientific Description
    AChE/BuChE/MAO-B-IN-1 (compound 19) is an inhibitor of human acetyl- (hAChE), butyrylcholinesterase (hBuChE) and monoamine oxidase-B (hMAO-B) with IC50s of 4.8 microM, 13.7 microM, and 1.11 microM, respectively. AChE/BuChE/MAO-B-IN-1 also exhibits high affinity to both the sigma1 and sigma2 receptors with Ki values of 42.8 nM (human sigma1 receptor) and 191 nM (rat sigma2 receptor), respectively. AChE/BuChE/MAO-B-IN-1 can be used for Alzheimers disease research[1].
  • SMILES
    O=C1CCOC2=C1C=C(OCCN3CCCCCC3)C=C2
  • UNSPSC
    12131703