AChE/BuChE/MAO-B-IN-2

MedChem Express

AChE/BuChE/MAO-B-IN-2

14

Research Use Only

C19H18FNO3

327.35

AChE/BuChE/MAO-B-IN-2 (compound 4b) is a potent AChE/BuChE inhibitor and showed good blood brain barrier (BBB) permeability in vitro with an IC50 value of 5.3 microM, 12.4 microM, 1.9+/-0.08 microM, for AChE, BuChE, huMAO-B, respectively. AChE/BuChE/MAO-B-IN-2 (compound 4b) can inhibit excess AChE/BuChE in Alzheimers disease (AD) brain. AChE/BuChE/MAO-B-IN-2 (compound 4b) can be used in anti-Alzheimers research[1].

CCN(C)C(OC1=CC=CC=C1C(/C=C/C2=CC=C(F)C=C2)=O)=O

12131703