Chemical Structure
Chemical Structure
Acid-PEG4-Val-Cit-PAB-MMAE
82276
Estimated Purity≥98%
Product group Chemicals
Molecular Weight1399.7 Da
Overview
- SupplierBPS Bioscience
- Product NameAcid-PEG4-Val-Cit-PAB-MMAE
- Delivery Days Customer7
- CertificationResearch Use Only
- Estimated Purity≥98%
- Molecular FormulaC70H114N10O19
- Molecular Weight1399.7 Da
- Scientific DescriptionAcid-PEG4-Val-Cit-PAB-MMAE is a cleavable ADC linker featuring a carboxylic acid, a hydrophilic PEG spacer, and a Val-Cit-PAB dipeptide ligated to an MMAE payload. Carboxylic acids are reactive towards amines or alcohols while the Val-Cit-PAB motif is an enzyme-cleavable linker. This linker efficiently releases the toxin, MMAE, to target cells to cause cellular apoptosis.
- Storage Instruction-20°C
- UNSPSC12352200