Acinus antibody

GeneTex

Acinus antibody

9

WB: 1-10microg/ml. ICC/IF: 5-10microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

Unconjugated

ACIN1

apoptotic chromatin condensation inducer 1

ACINUS; ACN; apoptotic chromatin condensation inducer in the nucleus; fSAP152; functional spliceosome-associated protein 152

Rabbit

IgG

Apoptotic chromatin condensation inducer in the nucleus

Apoptosis is defined by several morphologic nuclear changes, including chromatin condensation and nuclear fragmentation. This gene encodes a nuclear protein that induces apoptotic chromatin condensation after activation by caspase-3, without inducing DNA fragmentation. This protein has also been shown to be a component of a splicing-dependent multiprotein exon junction complex (EJC) that is deposited at splice junctions on mRNAs, as a consequence of pre-mRNA splicing. It may thus be involved in mRNA metabolism associated with splicing. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011]

-20°C or -80°C,2°C to 8°C

12352203