Ack1 inhibitor 1 [2924415-92-7]

TargetMol Chemicals

Ack1 inhibitor 1 [2924415-92-7]

16

Research Use Only

C39H40F3N7O4

727.77

Ack1 inhibitor 1 is a potent and selective orally active inhibitor of ACK1 kinase, with an IC50 value of 2.1 nM. It effectively inhibits the phosphorylation of ACK1 and the activation of downstream AKT, demonstrating anti-tumor activity [1].

C(N1C=2C(C=C(C1=O)C3=CC(NC(=O)C4=CC(C(F)(F)F)=CC=C4)=CC=C3)=CN=C(NC5=C(OCC)C=C(C=C5)N6CCN(C)CC6)N2)[C@H]7CCCO7

-20°C

51202000