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ACKR3, Human (His-SUMO)

Name: ACKR3, Human (His-SUMO)
SKU: HY-P700537_M09
Availability: BackOrder

HY-P700537

Protein IDP25106

Product group Proteins / Signaling Molecules

Overview

Supplier
MedChem Express
Product Name
ACKR3, Human (His-SUMO)
Delivery Days Customer
10
Certification
Research Use Only
Estimated Purity
96.0
Gene ID57007
Target name
ACKR3
Target description
atypical chemokine receptor 3
Target synonyms
atypical chemokine receptor 3; chemokine (C-X-C motif) receptor 7; chemokine orphan receptor 1; CMKOR1; C-X-C chemokine receptor type 7; CXCR7; CXC-R7; CXCR-7; G protein-coupled receptor; GPR159; G-protein coupled receptor 159; G-protein coupled receptor RDC1 homolog; RDC1; RDC-1
Protein IDP25106
Protein Name
Atypical chemokine receptor 3
Scientific Description
ACKR3 is an atypical chemokine receptor that precisely controls chemokine levels and localization through high-affinity binding, operating independently of ligand-driven signaling. It acts as an interceptor, internalization receptor, and chemokine scavenger for CXCL11 and CXCL12/SDF1, inducing beta-arrestin recruitment, ligand internalization, and MAPK pathway activation. ACKR3 Protein, Human (His-SUMO) is the recombinant human-derived ACKR3 protein, expressed by E. coli , with N-SUMO, N-6*His labeled tag.
Storage Instruction
-20°C
UNSPSC
41116100