Aclacinomycin A

MedChem Express

Aclacinomycin A [57576-44-0]

10

57576-44-0

Research Use Only

98.95

C42H53NO15

811.87

Aclacinomycin A (Aclarubicin) is an orally active and potent anthracycline antitumor antibiotic . Aclacinomycin A is an inhibitor of topoisomerase I and II . Aclacinomycin A inhibits synthesis of nucleic acid, especially RNA . Aclacinomycin A might inhibit the 26S protease complex as well as the ubiquitin-ATP-dependent proteolysis [1] [2] [3] .

O=C([C@@H]1C2=CC(C(C3=CC=CC(O)=C43)=O)=C(C4=O)C(O)=C2[C@@H](O[C@@](O[C@@H](C)[C@H]5O[C@@](O[C@@H](C)[C@H]6O[C@](CCC7=O)([H])O[C@H]7C)([H])C[C@@H]6O)([H])C[C@@H]5N(C)C)C[C@]1(O)CC)OC

2°C to 8°C

41116134