ACMSD antibody [N2C3]
GTX106739
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetACMSD
Overview
- SupplierGeneTex
- Product NameACMSD antibody [N2C3]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.86 mg/ml
- ConjugateUnconjugated
- Gene ID130013
- Target nameACMSD
- Target descriptionaminocarboxymuconate semialdehyde decarboxylase
- Target synonyms2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; picolinate carboxylase
- HostRabbit
- IsotypeIgG
- Protein IDQ8TDX5
- Protein Name2-amino-3-carboxymuconate-6-semialdehyde decarboxylase
- Scientific DescriptionThe neuronal excitotoxin quinolinate is an intermediate in the de novo synthesis pathway of NAD from tryptophan, and has been implicated in the pathogenesis of several neurodegenerative disorders. Quinolinate is derived from alpha-amino-beta-carboxy-muconate-epsilon-semialdehyde (ACMS). ACMSD (ACMS decarboxylase; EC 4.1.1.45) can divert ACMS to a benign catabolite and thus prevent the accumulation of quinolinate from ACMS.[supplied by OMIM]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
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