ACMSD antibody [N2C3]

GeneTex

ACMSD antibody [N2C3]

9

WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

0.86 mg/ml

Unconjugated

ACMSD

aminocarboxymuconate semialdehyde decarboxylase

2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; picolinate carboxylase

Rabbit

IgG

2-amino-3-carboxymuconate-6-semialdehyde decarboxylase

The neuronal excitotoxin quinolinate is an intermediate in the de novo synthesis pathway of NAD from tryptophan, and has been implicated in the pathogenesis of several neurodegenerative disorders. Quinolinate is derived from alpha-amino-beta-carboxy-muconate-epsilon-semialdehyde (ACMS). ACMSD (ACMS decarboxylase; EC 4.1.1.45) can divert ACMS to a benign catabolite and thus prevent the accumulation of quinolinate from ACMS.[supplied by OMIM]

Human, Mouse

-20°C or -80°C,2°C to 8°C

12352203