ACMSD Polyclonal Antibody
RD75418A
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman, Mouse
TargetACMSD
Overview
- SupplierReddot Biotech
- Product NameACMSD Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.2 mg/ml
- ConjugateUnconjugated
- Gene ID130013
- Target nameACMSD
- Target descriptionaminocarboxymuconate semialdehyde decarboxylase
- Target synonyms2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; picolinate carboxylase
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThe neuronal excitotoxin quinolinate is an intermediate in the de novo synthesis pathway of NAD from tryptophan, and has been implicated in the pathogenesis of several neurodegenerative disorders. Quinolinate is derived from alpha-amino-beta-carboxy-muconate-epsilon-semialdehyde (ACMS). ACMSD (ACMS decarboxylase; EC 4.1.1.45) can divert ACMS to a benign catabolite and thus prevent the accumulation of quinolinate from ACMS.
- ReactivityHuman, Mouse
- Storage Instruction-20°C
- UNSPSC12352203