ACOT8 antibody detects ACOT8 protein by western blot analysis. Rat tissue extracts (50 μg) was separated by 10 % SDS-PAGE, and the membrane was blotted with ACOT8 antibody (GTX103960) diluted by 1:1000.
ACOT8 antibody detects ACOT8 protein by western blot analysis. Rat tissue extracts (50 μg) was separated by 10 % SDS-PAGE, and the membrane was blotted with ACOT8 antibody (GTX103960) diluted by 1:1000.
ACOT8 antibody [N1C3]
GTX103960
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetACOT8
Overview
- SupplierGeneTex
- Product NameACOT8 antibody [N1C3]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID10005
- Target nameACOT8
- Target descriptionacyl-CoA thioesterase 8
- Target synonymsHNAACTE, NAP1, PTE-1, PTE-2, PTE1, PTE2, hACTE-III, hTE, acyl-coenzyme A thioesterase 8, HIV-Nef associated acyl-CoA thioesterase, Nef (lentivirus myristoylated factor) associated protein 1, choloyl-CoA hydrolase, choloyl-coenzyme A thioesterase, long-chain fatty-acyl-CoA hydrolase, palmitoyl-CoA hydrolase, peroxisomal acyl-CoA thioesterase 1, peroxisomal acyl-CoA thioesterase 2, peroxisomal acyl-coenzyme A thioester hydrolase 1, peroxisomal long-chain acyl-CoA thioesterase 1, thioesterase II, thioesterase III
- HostRabbit
- IsotypeIgG
- Protein IDO14734
- Protein NameAcyl-coenzyme A thioesterase 8
- Scientific DescriptionThe protein encoded by this gene is a peroxisomal thioesterase that appears to be involved more in the oxidation of fatty acids rather than in their formation. The encoded protein can bind to the human immunodeficiency virus-1 protein Nef, and mediate Nef-induced down-regulation of CD4 in T-cells. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- You BJ, Hour MJ, Chen LY, et al. Fenofibrate induces human hepatoma Hep3B cells apoptosis and necroptosis through inhibition of thioesterase domain of fatty acid synthase. Sci Rep. 2019,9(1):3306. doi: 10.1038/s41598-019-39778-yRead this paper
- You BJ, Chen LY, Hsu PH, et al. Orlistat Displays Antitumor Activity and Enhances the Efficacy of Paclitaxel in Human Hepatoma Hep3B Cells. Chem Res Toxicol. 2019,32(2):255-264. doi: 10.1021/acs.chemrestox.8b00269Read this paper
Datasheet
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