
IHC image of CSB-PA001170LA01HU diluted at 1:100 and staining in paraffin-embedded human liver tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
ACOT8 Antibody
CSB-PA001170LA01HU
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
TargetACOT8
Overview
- SupplierCusabio
- Product NameACOT8 Antibody
- Delivery Days Customer20
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID10005
- Target nameACOT8
- Target descriptionacyl-CoA thioesterase 8
- Target synonymsacyl-coenzyme A thioesterase 8; choloyl-CoA hydrolase; choloyl-coenzyme A thioesterase; hACTE-III; HIV-Nef associated acyl-CoA thioesterase; HNAACTE; hTE; long-chain fatty-acyl-CoA hydrolase; NAP1; Nef (lentivirus myristoylated factor) associated protein 1; palmitoyl-CoA hydrolase; peroxisomal acyl-CoA thioesterase 1; peroxisomal acyl-CoA thioesterase 2; peroxisomal acyl-coenzyme A thioester hydrolase 1; peroxisomal long-chain acyl-CoA thioesterase 1; PTE1; PTE-1; PTE2; PTE-2; thioesterase II; thioesterase III
- HostRabbit
- IsotypeIgG
- Protein IDO14734
- Protein NameAcyl-coenzyme A thioesterase 8
- Scientific DescriptionAcyl-coenzyme A (acyl-CoA) thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH (PubMed: 9299485, PubMed: 9153233, PubMed: 15194431). Competes with bile acid CoA: amino acid N-acyltransferase (BAAT) for bile acid-CoA substrate (such as chenodeoxycholoyl-CoA). Shows a preference for medium-length fatty acyl-CoAs (C2 to C20) (PubMed: 9299485, PubMed: 9153233). Inactive towards substrates with more than C20 aliphatic chains (PubMed: 9153233). Involved in the metabolic regulation of peroxisome proliferation (PubMed: 15194431).
- Storage Instruction-20°C or -80°C
- UNSPSC12352203