Actinomycin X2 [18865-48-0]

Bioss

Actinomycin X2 [18865-48-0]

16

18865-48-0

Research Use Only

Unconjugated

>98%

C62H84N12O17

1269.4

Aniso-Actinomycin (4-Oxopro instead of Pro in the beta-chain). Antitumor and antiviral antibiotic. Antituberculosis agent. Has higher cytotoxicity towards cultured human leukemia (HL-60) cells than actinomycin D. Apoptosis inducer. Forms a complex with DNA and blocks its biological activity.

[H][C@]12CCCN1C(=O)[C@H](NC(=O)[C@H](NC(=O)C1=C3N=C4C(OC3=C(C)C=C1)=C(C)C(=O)C(N)=C4C(=O)N[C@@H]1[C@@H](C)OC(=O)[C@@H](C(C)C)N(C)C(=O)CN(C)C(=O)[C@@]3([H])N(CCC3=O)C(=O)[C@H](NC1=O)C(C)C)[C@@H](C)OC(=O)[C@@H](C(C)C)N(C)C(=O)CN(C)C2=O)C(C)C

-20°C

12161600