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Activin Receptor Type IC antibody

GTX103442
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
TargetACVR1C
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Overview

  • Supplier
    GeneTex
  • Product Name
    Activin Receptor Type IC antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID130399
  • Target name
    ACVR1C
  • Target description
    activin A receptor type 1C
  • Target synonyms
    activin A receptor, type IC; activin receptor type IC; activin receptor type-1C; activin receptor-like kinase 7; ACTR-IC; ACVRLK7; ALK7; ALK-7
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ8NER5
  • Protein Name
    Activin receptor type-1C
  • Scientific Description
    ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).[supplied by OMIM]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • ALK7 expression in prolactinoma is associated with reduced prolactin and increased proliferation. Principe M et al., 2018 Sep, Endocr Relat Cancer
    Read more

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