Activin Receptor Type IC antibody
GTX103442
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Rat
TargetACVR1C
Overview
- SupplierGeneTex
- Product NameActivin Receptor Type IC antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID130399
- Target nameACVR1C
- Target descriptionactivin A receptor type 1C
- Target synonymsactivin A receptor, type IC; activin receptor type IC; activin receptor type-1C; activin receptor-like kinase 7; ACTR-IC; ACVRLK7; ALK7; ALK-7
- HostRabbit
- IsotypeIgG
- Protein IDQ8NER5
- Protein NameActivin receptor type-1C
- Scientific DescriptionACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).[supplied by OMIM]
- ReactivityHuman, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- ALK7 expression in prolactinoma is associated with reduced prolactin and increased proliferation. Principe M et al., 2018 Sep, Endocr Relat CancerRead more