ACTL6B Polyclonal Antibody

Reddot Biotech

ACTL6B Polyclonal Antibody

5

1.74 mg/ml

ACTL6B

actin like 6B

53 kDa BRG1-associated factor B; actin-like protein 6B; actin-related protein Baf53b; ACTL6; arpNalpha; BAF53B; BRG1-associated factor 53B; DEE76; EIEE76; hArpN alpha; IDDSSAD; SMARCN2

The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a subunit of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. This subunit may be involved in the regulation of genes by structural modulation of their chromatin, specifically in the brain. Alternative splicing results in multiple transcript variants.

-20°C

12352203