ACTL6B Polyclonal Antibody

Reddot Biotech

ACTL6B Polyclonal Antibody

5

ImmunoFluorescence, ImmunoHistoChemistry

Research Use Only

1 mg/ml

Unconjugated

ACTL6B

actin like 6B

ACTL6, BAF53B, DEE76, EIEE76, IDDSSAD, SMARCN2, arpNalpha, actin-like protein 6B, 53 kDa BRG1-associated factor B, BRG1-associated factor 53B, actin-related protein Baf53b, hArpN alpha

Rabbit

IgG

The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a subunit of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. This subunit may be involved in the regulation of genes by structural modulation of their chromatin, specifically in the brain. Alternative splicing results in multiple transcript variants.

-20°C

12352203