Acuitas Lipid A9

Biorbyt

Acuitas Lipid A9

10

Research Use Only

C57H112N2O5

905.51

Lipid A9 is an ionizable cationic lipid (pKa?= 6.27) that has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA and siRNA?in vivo.?LNPs containing lipid A9 and encapsulating non-stimulatory siRNA increase plasma levels of chemokine (C-C motif) ligand 2 (CCL2), indicating activation of the innate immune response, and decrease body weight in mice.

CCCCCCCCC(=O)N(CCCN(C)C)C(CCCCCCCCC(=O)OCC(CCCC)CCCCCC)CCCCCCCCC(=O)OCC(CCCC)CCCCCC

12352200