Acyclovir-d4

MedChem Express

Acyclovir-d4 [1185179-33-2]

10

1185179-33-2

Research Use Only

98.66

C8H7D4N5O3

229.23

Acyclovir-d 4 is the deuterium labeled Acyclovir. Acyclovir (Aciclovir) is a guanosine analogue and an orally active antiviral agent. Acyclovir inhibits HSV-1 (IC50 of 0.85 microM), HSV-2 (IC50 of 0.86 microM) and varicella-zoster virus. Acyclovir can be phosphorylated by viral thymidine kinase (TK), and Acyclovir triphosphate interferes with viral DNA polymerization through competitive inhibition with guanosine triphosphate and obligatory chain termination[1][2][3]. Acyclovir prevents bacterial infections during induction therapy for acute leukaemia[4].

O=C1NC(N)=NC2=C1N=CN2COC([2H])([2H])C([2H])([2H])O

-20°C

12352200